CRYOcheck™ Lupus Negative Control

 

Plasma negative for lupus anticoagulant (LA) assays.

CRYOcheck™Lupus Negative Lupus Negative Quality Control Plasma is prepared from plasmas of healthy patients without anticoagulant lupus.
Recommended as a negative control for lupus anticoagulant testing.


Advantages

- Easily adaptable, the reagent is designed for use on most hemostasis analyzers.
- Ready to use.


Informations

Lupus anticoagulants (LA) are heterogeneous autoantibodies of the IgG and IgM type directly directed against a variety of anionic phospholipids such as cardiolipin, phosphatidylserine or phosphatidylinositol or against proteins having the capacity to bind to phospholipids such as β2-glycoprotein I (β2-GPI).

The presence of LA is primarily detected using sensitive in vitro assays using phospholipids, such as TCA ( Activated cephalin) or dRVVT. They have the in vitro capacity to prolong phospholipid-dependent clotting times but are most often associated with thrombotic complications in vivo (venous or arterial thrombosis, thrombocytopenia and fetal losses) and do not predispose to a risk of bleeding.
DRVVT is routinely used in screening for LA. It is considered specific and robust.


Documentation

Download the product sheet
Price list, safety data sheets and notices are accessible to our registered customers.


Chronometric assay
 
 
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References

CCLN-10Kit25 x 1.0 mL
CCLN-05Kit25 x 0.5 mL