HEMOSTASIS COAGULATION ROUTINE REAGENTS SCREENING TESTS PT APTT FIBRINOGEN TT
Fibrinogen Reagent Kit
Fibrinogen assay based on the (modified) Clauss method.
For this routine hemostasis test, the clotting time of the diluted citrated plasma is determined in the presence of excess thrombin (≈ 80 IU / mL) and a reaction accelerator.
Informations
Fibrinogen (Factor I) is a plasma soluble glycoprotein that is synthesized by the liver at a size of 340 kDa and circulating at a concentration of 2.6 to 3 mg/mL.
Fibrinogen is a dimer bound by disulfide bridges composed of 3 pairs of polypeptide chains not identical. Under the action of thrombin, fibrinogen is converted into fibrin. In combination with FXIII, calcium ions, fibrin forms a stable network that ensures coagulation.
Documentation
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Chronometric assay
References
| 4-5138005 | Kit | 45 tests |
