Fibronectin protein

 
Formulation : 0.05M Tris, 0.15M NaCl, 0.03% NaN3, pH 7.4

From human plasma
MW(Da) : 440 000 without reduction (double chain) and 22 000 in reduced condition.



Informations

Fibronectin is a glycoprotein that exists in soluble form in plasma or in fibrillar form in the extracellular matrix. This protein modulates the interactions between cells and the extracellular matrix. In the absence of fibrinogen, fibronectin controls coagulation. Fibronectin can bind to fibrin to strengthen clots and make them more stable. Fibronectin has shown roles in platelet function, fibrinolysis, chemotaxis, phagocytosis, and opsonization. In certain pathologies such as trauma, sepsis, liver disorders, the fibronectin level may be low. Conversely, some cancers can have high fibronectin levels.


Documentation

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References

4-TC41150Vial1 mg