High Factor II plasma (G20210A positive mutation) > 150%

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The polymorphism of the prothrombin gene associated with a moderate hereditary thrombophilia corresponds to the replacement of a guanine by an adenine at position 20210, (3 'non-coding region of the prothrombin gene). The prothrombin level is on average higher. The frequency of this gene variation is 2% in the general population of Caucasian origin and 7% in patients with a history of venous thromboembolism.