HEMOSTASIS COAGULATION RESEARCH REAGENTS COFACTORS FIBRONECTIN
 
 

Human fibronectin

 

Formulation : 20 mM HEPES, 150 mM NaCl, pH 7.4

MW(Da) : 550 000
Extinction coef. : 14
Point isoéléctrique : approx. 5.0
Structure : hétérodimère


Advantages

The vast majority of coFactors is pure (without additives) with > 95 % purity SDS-PAGE.
Expiration date of one year from delivery.
Delivery in large quantities.
Discount according to quantities.


Informations

A cofactor is a chemical substance, which binds to a protein, and which is necessary for the biological activity of the latter. These proteins are often enzymes, and cofactors can be thought of as "helper molecules" aiding in biochemical transformations. Fibronectin is a glycoprotein that exists in soluble form in plasma or in fibrillar form in the extracellular matrix. This protein modulates the interactions between cells and the extracellular matrix. In the absence of fibrinogen, fibronectin controls cogulation. Fibronectin can bind to fibrin to strengthen clots and make them more stable. Fibronectin has shown roles in platelet function, fibrinolysis, chemotaxis, phagocytosis, and opsonization. In certain pathologies such as trauma, sepsis, liver disorders, the fibronectin level may be low. Conversely, some cancers can have high fibronectin levels.


Documentation

Download the product sheet
Price list, safety data sheets and notices are accessible to our registered customers.


 
 
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References

9-HCFN-0170Vial2 mg
9-HCFN-0170-1Vial1 mg