HEMOSTASIS COAGULATION RESEARCH REAGENTS ENZYMES KALLIKREIN
 
 

Human kallikrein

 

Structure : 52 kDa heavy chain and a 33 kDa light chain linked by disulfide bridges.
Formulation : 1mg in a buffer composed of 4mM sodium acetate / hydrochloride, 150mM NaCl, pH 5.3

MW(Da) : 85 000
Coef. Extinction : 1.17



Informations

Kallikrein is a glycoprotein derived from prekallikrein. It is non-covalently complexed to the high molecular weight kininogen. FXIIa activates the transformation of prekallikrein into kallikrein which will activate FXII and hydrolyze KHPM into several fragments. In fibrinolysis, kallikrein is also able to activate pro-urokinase to urokinase.


Documentation

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References

11-473Vial1 mg