HEMOSTASIS COAGULATION RESEARCH REAGENTS COFACTORS PROTEIN S
Human protein S
Human protein S
Formulation : Glycérol 50% / H₂O (v/v)
MW(Da) : 69 000
Concentration : 6.1 mg/mL
Extinction coef. : 9.5
Isoelectric point : 5.0-5.5
Structure: single chain, Gla domain in NH2-terminal and 4 EGF domains
Advantages
The vast majority of coFactors is pure (without additives) with > 95 % purity SDS-PAGE.
Expiration date of one year from delivery.
Delivery in large quantities.
Discount according to quantities.
Informations
A cofactor is a chemical substance, which binds to a protein, and which is necessary for the biological activity of the latter. These proteins are often enzymes, and coFactors can be thought of as "helper molecules" aiding in biochemical transformations. Protein S is a 69 kDa-dependent vitamin K eglycoprotein synthesized by hepatocytes, endothelial cells, megakaryodytes and osteoblasts. It is a physiological inhibitor of coagulation.
Protein S acts as a cofactor of activated protein C by promoting the inactivation by proteaolysis of factors Va and VIIIa.
Protein S inhibits the activation of prothrombin and the formation of the prothrombinase complex on phospholipids as well as the activation of FX.
Documentation
Download the product sheetPrice list, safety data sheets and notices are accessible to our registered customers.
References
| 9-HCPS-0090 | Vial | 100 µg |
| 9-HCPS-0090-1 | Vial | 1 mg |
