HEMOSTASIS COAGULATION RESEARCH REAGENTS MONOCLONAL ANTIBODIES ANTI-VITRONECTIN
Mouse monoclonal antibody anti-vitronectin, 2VN, IgG
Human vitronectin
Application : Immunoblotting, ELISA
Host : Mouse
Immunogen: purified human vitronectin
Informations
Vitronectin (Vn) is an adhesive glycoprotein, synthesized by the liver, released in plasma and present in the extracellular matrix. Vn binds PAI-1. This complex fully activates PAI-1, unlike PAI-1 in solution, where it does not appear to be stable and inactive. Vn therefore seems to regulate the enzymatic specificity of PAI-1, by stabilizing it. Decreased Vn levels occur in DICs and liver disease (cirrhosis). Vn deposition is associated with atherosclerotic lesions.
Documentation
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References
| 4-TC21511 | Vial | 500 µg |
