HEMOSTASIS COAGULATION RESEARCH REAGENTS ZYMOGENS PLASMINOGEN
Mouse plasminogen
MW(Da) : 88 000
Extinction coef. : 17.0
Structure : single chain with 24 intrachain disulfide bridges, 5 kringle regions.
Advantages
The vast majority of zymogens is pure (without additives) with > 95 % purity SDS-PAGE.
No additive or preservative.
Informations
A proenzyme or zymogen is a protein precursor of an enzyme which can give, after activation, an active enzyme. Plasminogen (88 kDa) is the zymogen of plasmin, a key enzyme in the fibrinolysis system.
Plasminogen is synthesized mainly by the liver but also the eosinophils, the kidney and the cornea.
Plasminogen exists in 2 molecular forms: glu-plasminogen (native form) and lys-plasminogen (more active form).
The main pathways for activating plasminogen to plasmin involve t-PA and u-PA.
The 2 carbohydrate variants of glu-plasminogen (CHOI and CHOII) are isolated by a gradient elution on sepharose-lysine using a lysine analogue (aminocaproic acid).
Documentation
Download the product sheetPrice list, safety data sheets and notices are accessible to our registered customers.
References
9-MCPG-5130 | Vial | > 1 mg |