HEMOSTASIS COAGULATION RESEARCH REAGENTS MONOCLONAL ANTIBODIES ANTI-FACTOR VIII
Murine monoclonal antibody against human FVIII, heavy chain, clone ESH-5
The antibody is purified from cell cultures via Protein G affinity chromatography. Purified human Factor VIII:C cryoprecipitate was used as an immunizing antigen.
Applications : Immunoblotting, inhibition, immunohistochemistry, immunopurification and immunodepletion.
Source : Human.
Immunogen: human urokinase.
Advantages
Factor VIII is a glycoprotein synthesized primarily by the liver. It circulates in plasma in a VWF-bound form that protects it from rapid proteolytic degradation.
It is activated by FXa or thrombin in FVIIIa which will be complexed with FIXa in the presence of phospholipids to activate FX in FXa.
The mature form of FVIII is a single-chain protein with a molecular ratio of about 265 kDa.
Documentation
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References
| 26-ADGESH-5 | Vial | 1 x 0,5 mg |
