Protein C Immunodepleted Deficient Human Plasma 

 

Immunodepleted deficient plasma for protein C assay

Pooled normal citrated human plasma depleted of protein C using antibodies directed
to protein C immobilized on agarose beads. Plasma contains 20 mM Hepes.


Advantages

- No bovine additives
- No reconstitution error
- No deterioration of plasmas linked to freeze-drying
- Cryotubes ready to use after thawing (4 min at 37°C).


Informations

Protein C is a 62 kDa glycoprotein, synthesized by the liver in the presence of vitamin K. CP is at the center of a physiological system that inhibits coagulation: the anticoagulant system of protein C. Thrombin associated with thrombomodulin loses its procoagulant properties at the same time as it activates PC to active protein C (PCa).

PCa in the presence of protein S, calcium and phospholipids is capable of cleaving FVa and FVIIIa blocking the amplification loop of thrombin generation.


Documentation

Download the product sheet
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Fresh frozen plasmas
 
 
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References

6-FDPPC-10Kit10 x 1.0 mL
6-FDPPCBottle1 x 100 mL