HEMOSTASIS COAGULATION RESEARCH REAGENTS PLASMA DERIVED PROTEINS FIBRINOGEN
Purified human fibrinogen
Highly purified fibrinogen extracted from citrated human plasma.
The vial contains at least 5 mg of purified human fibrinogen.
Advantages
Vial containing at least 5 mg of purified human fibrinogen. Main band of 340,000 daltons on SDS-PAGE.
This fibrinogen has a coagulability ≥ 98%
Informations
Fibrinogen (Factor I) is a soluble glycoprotein in blood plasma which is synthesized by the liver with a size of 340 kDa and circulating at a concentration of 2.6 to 3 mg/mL. Fibrinogen is a dimer linked by disulfide bridges composed of 3 pairs of non-identical polypeptide chains. Under the action of thrombin, fibrinogen is converted into fibrin. In association with FXIII, calcium ions, fibrin forms a stable network which ensures coagulation. The degradation products of the fibrinogen end produce Fragments D and E. Fragment D corresponds to the globular domains of fibrinogen, or fragment E corresponds to the amino acids of the N-terminal domain of the disulfide - knot domain.
Documentation
Download the product sheetPrice list, safety data sheets and notices are accessible to our registered customers.
References
| 6-FIB-5 | Vial | 1 x 5 mg |
