HEMOSTASIS COAGULATION RESEARCH REAGENTS PLASMA DERIVED PROTEINS TISSUE FACTOR
Recombinant human tissue factor
Formulation: lyophilized protein in a 10 mM Tris-HCl buffer, 150 mM NaCl, 0.01% CHAPS, pH 8, 200 mM Mannitol.
Whole recombinant human FT.
Animated acids 1 to 263 including the extracellular, transmembrane, cytoplasmic domains.
MW(Da) : 35 000 (38 kDa band under reduced conditions)
Advantages
The lyophilized presentation allows greater stability until the expiration date.
Informations
Tissue factor (FT) is a transmembrane glycoprotein which is primarily responsible for activating coagulation cascades in the event of a vascular breach.
The binding of FVII to its receptor, expressed by the cells of the subendothelium exposed by the lesion, allows its very rapid activation by traces of FXa, circulating in trace amounts in vivo.
The FT-FVIIa complex then causes the activation of FIX and FX and the formation of thrombin.
Documentation
Download the product sheetPrice list, safety data sheets and notices are accessible to our registered customers.
References
| 11-4500 | Vial | 25 μg |
