HEMOSTASIS COAGULATION RESEARCH REAGENTS VENOM PROTEASES VIPERA RUSSELII VENOM
RVV-V Venin de Vipèra Russelii (lyophilized)
Product derived from the venom of Vipera russelli in lyophilized form.
500 à 1000 U MW(Da) : 28 000 RVV-V is a specific FV activator from Russell’s viper venom converts single chain FV to an active two chain form. Activated FV is not stable and loses its activity within 20 hours at 37° C. Therefore, RVV-V is used to destabilize and selectively inactivate FV in plasma and thus to prepare a routine reagent for the FV determination.
Advantages
The venom proteases offered are highly purified, homogenous preparations with the indicated activities.
Informations
Snake venom proteases are useful tools for studying coagulation reactions. Venoms contain more than 20 different compounds, mostly proteins and polypeptides. Some of the proteins in snake venom have very specific effects on various biological functions including blood coagulation, blood pressure regulation, transmission of the nervous or muscular impulse and have been developed for use as diagnostic tools. Plasma coagulation Factors are usually inactive and require proteolytic activation as a first step towards a chronometric or colorimetric assay. It is often advantageous to use specific enzymes from snake venoms to activate coagulation Factors rather than physiological activators. In contrast to other activators, many snake venom enzymes are not dependent from cofactors, phospholipid or calcium ions.
Documentation
Download the product sheetPrice list, safety data sheets and notices are accessible to our registered customers.
References
| 6-VEN-RVVV-100 | Vial | 100 µg |
