Solcoll Collagen Solution

Solcoll can also be used to trigger platelet aggregation in whole blood impedance tests. It is in the form of a relatively stable, slightly cloudy and viscous liquid suspension of 200 μg / ml in 0.02 M of tris / HEPES glucose buffer at pH 7.2.
The 100 µg / ml stock solution can be diluted in water, saline, or neutral buffer of lower ionic strength to any desired collagen concentration.
A range between 1 and 10 µg / ml is usually prepared for light transmission aggregometry (LTA).
Platelet aggregation is usually performed with a dilution of 0.45 ml of platelet rich plasma and 0.05 ml of collagen although proportionately smaller volumes can be used.