Very Low XII Control Plasma

 

Control plasma to measure the accuracy of the quantitative determination of Factor XII in hemostasis for a very low value.

This low value control is titrated for Factor XII hemostasis values around 2%.



Informations

Factor XII is a glycoprotein synthesized by the liver, zymogen of a serine protease. Its plasma half-life is 50 to 70 hours. This factor participates in the contact phase which initiates the intrinsic pathway of coagulation.
Activated on contact with a negatively charged surface, it becomes capable of activating prekallikrein to kallikrein, then FXI to FXIa in the presence of KHPM.
It is also able to activate plasminogen into plasmin.


Documentation

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Fresh frozen plasmas
 
 
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References

6-VL12C-05Kit25 x 0.5 mL