Human Activated Protein C

 

Origin : Human Blood / Plasma
Determination of activity by chromogenic test
2-chain structure : molecular weight 35 000 and 21 000 Da, Gla domain in N-terminal and 2 EGF domains

Molecular weight (Da) : 56 200
Extinction coef. : 14.5
Buffer formulation : 50/50 (v/v) glycérol/H₂O

 


Advantages

The vast majority of enzymes is pure (without additives) with > 95% purity SDS-PAGE.
Expiration date of one year from delivery.
Delivery in large quantities
Discount according to quantities


Informations

An enzyme is a protein that catalyzes a biochemical reaction. It converts a substrate into a product. Each enzyme has a structure adapted to its function and its activity is dependent on an optimum temperature and pH. Protein C is a 62 kDa glycoprotein, synthesized by the liver in the presence of vitamin K. PC is at the center of a physiological system that inhibits coagulation : the anticoagulant system of protein C. Thrombin associated with thrombomodulin loses its procoagulant properties at the same time as it activates PC to active protein C (PCa). PCa in the presence of protein S, calcium and phospholipids is capable of cleaving FVa and FVIIIa blocking the amplification loop of thrombin generation.


Documentation

Download the product sheet
Price list, safety data sheets and notices are accessible to our registered customers.


 
 
congeleRUObioHazardstockage_-25_-15Cimportateurdistributeur
 

References

9-HCAPC-0080Vial50 µg
9-HCAPC-0080-1Vial1 mg