HEMOSTASIS COAGULATION RESEARCH REAGENTS INHIBITORS NATURAL PROTEASE INHIBITORS
Mouse antithrombin
Formulation : 50/50 (v/v) glycerol/H₂O
Inactivates several serine proteinases
Activity : 0.6 to 1.0 mole thrombin / mole AT
MW(Da) : 58 000
Extinction coef. : 6.2
Isoelectric point: 4.9-5.3
Structure: single chain, 3 intrachain disulfide bonds, 10% alpha-helise, 30-40% structure-beta, 50% random coil, scissile bond
Advantages
Supplied lyophilized or frozen.
Expiry date > 1 year.
Glass vial or plastic tubes.
Discount according to quantities.
Informations
Antithrombin is a glycoprotein of the serpin family, synthesized by the liver with a half-life of 3 days.
It is the most potent of the physiological inhibitors of coagulation.
It mainly inhibits thrombin but also at a lower level FIXa, FXa, FXIa.
Its inhibitory action is amplified in the presence of heparin or heparan sulfate.
Documentation
Download the product sheetPrice list, safety data sheets and notices are accessible to our registered customers.
References
| 9-MCATIII-5120 | Vial | > 1 mg |
