HEMOSTASIS COAGULATION RESEARCH REAGENTS POLYCLONAL ANTIBODIES ANTI-VITRONECTIN
Rabbit polyclonal antibody anti-human vitronectin
Antigen : vitronectin and complexes with PAI-1, no reaction with other plasma proteins.
Application : ELISA
Host : Rabbit
Informations
Vitronectin (Vn) is an adhesive glycoprotein, synthesized by the liver, released in plasma and present in the extracellular matrix. Vn binds PAI-1. This complex fully activates PAI-1, unlike PAI-1 in solution, where it does not appear to be stable and inactive. Vn therefore seems to regulate the enzymatic specificity of PAI-1, by stabilizing it. Decreased Vn levels occur in DICs and liver disease (cirrhosis). Vn deposition is associated with atherosclerotic lesions.
Documentation
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References
| 4-TC31054 | Vial | 1 mg |
