CRYOcheck™ Factor VIII Deficient Plasma with VWF

 

Human plasma deficient in Factor VIII with a normal level of von Willebrand factor (VWF), used for the search for inhibitors of Factor VIII. Immunodepleted, frozen and poor in platelets.

Factor VIII deficient plasma with a normal level of VWF for clinical laboratory use for the quantitative determination of Factor VIII (FVIII) activity in 3.2% citrated human plasma.


Advantages

- Ready to use after thawing, saves time.
- Convenient frozen format
- Ready to use quickly and without reconstitution errors.
- Protocol available on request.

The importance of VWF antigen levels in the performance of FVIII-deficient plasmas was demonstrated in a poster presented at ISTH 2021.


Informations

Factor VIII is a glycoprotein with a molecular weight of 250,000 Da synthesized mainly by the liver.
It circulates in the plasma in the form bound to VWF which protects it from rapid proteolytic degradation.
It is activated by FXa or thrombin in FVIIIa which will complex with FIXa in the presence of phospholipids to activate FX in FXa. A patient who is deficient in FVIII has hemophilia A.


Documentation

Download the product sheet
Price list, safety data sheets and notices are accessible to our registered customers.


Fresh frozen plasmas
 
 
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References

FDP08VWF-15Kit25 x 1.5 mL
FDP08VWF-10Kit25 x 1.0 mL